Make Caffeine Visible: a Fluorescent Caffeine “Traffic Light” Detector

Wang Xu, et al., Make Caffeine Visible: a Fluorescent Caffeine “Traffic Light” Detector, Scientific Report 3, 2013

Here we report a novel aqueous phase fluorescent caffeine sensor named Caffeine Orange which exhibits 250-fold fluorescence enhance upon caffeine activation and high selectivity.

To Utilize this probe in real life, we developed a non-toxic caffeine detection kit and tested it for caffeine quantification in various beverage. Naked-eye sensing of various caffeine concentrations was possible based on color changes upon irradiation with a laser pointer.

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