Sophie Lovell, Dieter Rams: As Little Design as Possible, Phaidon Press Inc., 2011
By omitting the unnecessary, says Rams, the essential factors come to the fore: the products become ‘quiet, pleasing, comprehensible and long-lasting’. However to arrive at products with this quality the designer has to travel a very long and difficult path filled with question, trials, discussion and experimentation. The product may be simple but the path taken to create it is highly complex for the ‘true’ product designer.
Marcus Flacks, Classical Chinese Furniture, The Vendome Press, 2012
The preaching daises of the Buddhist monks and the folding stools of the western nomads had a slow, but irrevocable effect on the Chinese… they ushered in raised level seating, eventually leading China to be the only culture in Asia to abandon floor seating.
Lars Feuerbach, et al., TelomereHunter: telomere content estimation and characterization from whole genome sequencing data, bioRxiv, 2016
Here, we present TelomereHunter, a new computational tool for determining telomere content that is specifically designed for matched tumor and control pairs. In contrast to existing tools, TelomereHunter takes alignment information into account and reports the abundance of variant repeats in telomeric sequences.
The criterion of searching for six non-consecutive repeats in 100bp long reads has been proposed previously (Lee, et al., 2014) and was also found suitable for the data presented in the present study.