Dieter Rams: As Little Design as Possible

Sophie Lovell, Dieter Rams: As Little Design as Possible, Phaidon Press Inc., 2011

By omitting the unnecessary, says Rams, the essential factors come to the fore: the products become ‘quiet, pleasing, comprehensible and long-lasting’. However to arrive at products with this quality the designer has to travel a very long and difficult path filled with question, trials, discussion and experimentation. The product may be simple but the path taken to create it is highly complex for the ‘true’ product designer.

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Classical Chinese Furniture

Marcus Flacks, Classical Chinese Furniture, The Vendome Press, 2012

The preaching daises of the Buddhist monks and the folding stools of the western nomads had a slow, but irrevocable effect on the Chinese… they ushered in raised level seating, eventually leading China to be the only culture in Asia to abandon floor seating.

Beyond Bar and Line Graphs: Time for a New Data Presentation Paradigm

Tracy L. Weissgerber TL, et al., Beyond Bar and Line Graphs: Time for a New Data Presentation Paradigm, PLoS Biol 13(4), 2015

Our systematic review of research articles published in top physiology journals (n = 703) suggests that, as scientists, we urgently need to change our practices for presenting continuous data in small sample size studies. Papers rarely included scatter- plots, box plots, and histograms that allow readers to critically evaluate continuous data. Most papers presented continuous data in bar and line graphs. This is problematic, as many different data distributions can lead to the same bar or line graph.

TelomereHunter: telomere content estimation and characterization from whole genome sequencing data

Lars Feuerbach, et al., TelomereHunter: telomere content estimation and characterization from whole genome sequencing data, bioRxiv, 2016

Here, we present TelomereHunter, a new computational tool for determining telomere content that is specifically designed for matched tumor and control pairs. In contrast to existing tools, TelomereHunter takes alignment information into account and reports the abundance of variant repeats in telomeric sequences.

 

The criterion of searching for six non-consecutive repeats in 100bp long reads has been proposed previously (Lee, et al., 2014) and was also found suitable for the data presented in the present study.